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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
4.55
Human Site:
Y132
Identified Species:
7.14
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
Y132
E
V
I
D
R
L
R
Y
L
K
A
E
I
E
D
Chimpanzee
Pan troglodytes
XP_511025
426
45548
E118
E
I
A
D
K
L
I
E
L
K
A
E
I
E
E
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
Y132
E
V
I
D
R
L
R
Y
L
K
A
E
I
E
D
Dog
Lupus familis
XP_853833
304
33793
E105
D
L
E
L
K
E
R
E
L
D
Q
Q
K
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
C122
E
V
I
D
R
L
R
C
L
K
A
E
I
E
D
Rat
Rattus norvegicus
Q62814
300
33206
Q105
K
E
R
E
L
D
Q
Q
K
L
W
L
Q
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
E31
D
L
D
L
K
E
R
E
L
D
Q
Q
K
S
W
Chicken
Gallus gallus
Q90977
403
43534
K185
S
R
Q
R
L
L
E
K
E
L
R
D
L
Q
A
Frog
Xenopus laevis
NP_001086706
375
40890
Q105
A
E
L
A
D
L
E
Q
R
E
Q
E
L
D
Q
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
E106
L
E
D
L
D
R
R
E
H
E
L
D
Q
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
D335
R
S
R
H
I
E
A
D
S
L
R
L
E
Q
Q
Honey Bee
Apis mellifera
XP_624285
300
34327
L105
L
E
D
H
E
Q
L
L
D
K
H
T
Q
W
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
L131
D
D
V
E
N
S
R
L
A
Y
V
T
H
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
L211
V
S
D
D
M
S
I
L
Q
A
D
I
D
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
Q248
D
A
D
V
S
V
L
Q
A
E
I
E
N
L
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
60
100
13.3
N.A.
93.3
0
N.A.
13.3
6.6
13.3
6.6
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
80
100
40
N.A.
93.3
26.6
N.A.
40
26.6
40
26.6
N.A.
6.6
6.6
N.A.
40
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
0
0
7
0
14
7
27
0
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
27
7
34
34
14
7
0
7
7
14
7
14
7
7
27
% D
% Glu:
27
27
7
14
7
20
14
27
7
20
0
40
7
34
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
14
0
0
0
0
7
0
7
0
7
0
0
% H
% Ile:
0
7
20
0
7
0
14
0
0
0
7
7
27
0
7
% I
% Lys:
7
0
0
0
20
0
0
7
7
34
0
0
14
0
0
% K
% Leu:
14
14
7
20
14
40
14
20
40
20
7
14
14
14
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
7
20
7
0
20
14
20
27
14
% Q
% Arg:
7
7
14
7
20
7
47
0
7
0
14
0
0
0
7
% R
% Ser:
7
14
0
0
7
14
0
0
7
0
0
0
0
7
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% T
% Val:
7
20
7
7
0
7
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
14
% W
% Tyr:
0
0
0
0
0
0
0
14
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _